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Clinical experience suggests that some individuals experience increased tiredness, particularly during treatment initiation or dose escalation

To meet the metabolic demand of immune cells, systemic metabolic remodeling is required

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In clinical trials in 675 patients, vemurafenib was associated with a rash in 18% of patients, photosensitivity in 12%, squamous cell carcinoma or keratoacanthoma in 18% to 26%, and alopecia in 8%

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